Psyk-out weapons have similar effects to Psycannon bolts; they are anti-psyker weapons. Psyk-out weapons take grenade and missile form.
When they detonate they release fine dust particles which are heavily impregnated with negative psychic energy. This form of energy is extremely rare; in all human space it can obtained only as a by-product of the Emperor's metabolism. Using the material to create anti-psyker weapons is considered by many to be a great waste, and their issue is strictly controlled.
Psyk-out weapons are useless against normal targets. Against psychic creatures such as daemons and psykers their effects are devastating.
They are utilised by Culexus assassins and by Witch Hunter armies (as orbital missiles).